Driving the Commercialization of University of Chicago Research

Building on University of Chicago’s breakthroughs

Harper Court Ventures invests in transformative technologies emerging from the University of Chicago—where world-class research fuels real-world ventures. We back pre-seed startups at the frontier of quantum computing, life sciences, energy, and AI—spun out of university labs, accelerated by the Polsky Center, or founded by University of Chicago alumni. Led by Chicago Booth alum, Karthee Madasamy and managed by MFV Partners, a leading Silicon Valley deep tech fund, we’re building a new engine of innovation for the Midwest—and beyond.

Driving the Midwest’s deep tech future.

ENERGY

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QUANTUM COMPUTING

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LIFE SCIENCES

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AI / DATA SCIENCES

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LIFE SCIENCES​

QUANTUM COMPUTING​

ENERGY

AI / DATA SCIENCES​

Our team brings together seasoned investors, technologists, and founders with decades of experience in scaling breakthrough innovation. From Silicon Valley to Chicago, we back visionary startups with the insight and support needed to lead in quantum, AI, life sciences, and energy.

Karthee Madasamy

Managing Partner

University of Chicago Booth alum and veteran deep tech investor with a track record in quantum, AI, energy, and robotics.
We invest in bold, early-stage startups emerging from the University of Chicago ecosystem. Each company in our portfolio is built on transformative research and positioned to lead in quantum, AI, life sciences, or energy.
Health, Life Sciences

2024

AI, Life Sciences

2025

Health, Life Sciences

2025

Explore the latest announcements, founder stories, and deep tech trends shaping our work. Stay informed on how Harper Court Ventures and our portfolio companies are driving innovation forward.